11 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... treatment #summary #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology ... #diagnosis #management
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... Variety #type #clinical ... #photo #foot #dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... mucositis - Rash ... vasculitis, and SLE ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... diseases, such as SLE ... , mucositis • Rash ... tract, and often causes ... #Rheumatology
Monkeypox Skin Rash
30 yr F and her 6 yr daughter purchased 2 prairie dogs 10 days
Monkeypox Skin Rash ... dogs 10 days ago (pers ... Diagnosis? ... Monkeypox #SkinRash #clinical ... #photo #dermatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... DrugInduced #Lupus #DIL #rheumatology ... #diagnosis #treatment