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diagnosis differential algorithm injury liver oncology anemia aplastic gap globulin hepatitis hypertension leukemia management portal prbc protein proteingap thresholds transfusion
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... C, A, E, B, D, EBV ... obstruction, HELLP Syndrome ... Differential #Diagnosis #Causes ... #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... and hepatorenal syndrome ... • Budd Chiari syndrome ... • Cirrhosis/acute ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... HBV, HCV, HEV, EBV ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... and petechiae Causes ... Constitutional Syndromes ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Cytopenia -> BM ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... HIV, HBV, EBV, ... gastric tumors • Hematology ... inflammation (acute ... differential #diagnosis #hematology
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