14 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Cytopenia -> BM ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... - Lupus - Leukemia
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
Leukemia/Lymphoblastic ... Lymphoma Clinical ... disease with limited BM ... involvement are skin ... Traditionally based age
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... Headaches • Pale skin ... and petechiae Causes ... ) • Leukemia
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
1) 4) Average age ... renal failure Clinical ... and progressive Acute ... nodes: 13-15%, skin ... : ACUTE, fever,
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... sweats (28%) • Skin ... rash (48%) • ... 14%), in which case ... Epstein-Barr virus (EBV
Acute Generalized Exanthematous Pustulosis (AGEP)

AGEP is largely a clinical diagnosis based on classical skin findings in
Acute Generalized ... a clinical diagnosis ... Causes? ... Clinical Presentation ... During the acute
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Classification: • Acute ... Clinical Features ... Hodgkin lymphoma and leukemia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... Takayasu: - Age ... temporal artery - Age
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Epidemiology: - Bimodal age ... Clinical Picture ... Clinical DX: - ... aspiration and acute ... immunosuppressants - Meds