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diagnosis rheumatology druginduced associated cardiomyopathy comparison dil erythematosus glomerulonephritis gn hemophagocytic hlh lymphohistiocytosis muscle myocarditis myopathy nephrology neurology palsy peripartum
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Usual therapeutic management
Myocarditis 5 Principles of Myocarditis: 1. Build clinical suspicion 2. Decide on EMBx 3. Manage acute cardiac injury 4. Manage chronic
Presentation: - Fever, Rash ... Low voltage Treatment ... Myocarditis #diagnosis #management ... #cardiology #summary ... #biopsy
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
Summary CLINICAL ... Nephritic syndrome (Casts ... • Vasculitic rash ... available • Renal biopsy ... deposits common TREATMENT
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Summary - GrepMed ... - Atypical Clinical ... systemic signs (rash ... CNS inflammatory cause ... #Treatment #Neurology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... GBS), systemic lupus ... erythematosus (SLE ... IMNM) • Muscle biopsy ... myopathy #diagnosis #management
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... Clinical • Under-recognized ... orthopnea, PND, LE ... #cardiology #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary gland) biopsy ... ducts Clinical ... Adenocarcinoma Treatment ... Rheumatology #Diagnosis #Management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... #management
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