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diagnosis disease syndrome adultonset aosd druginduced giantcell hemophagocytic lupus lymphohistiocytosis signs symptoms 2ndline activation antinxp2 antinxp2dm behcet behcets classification comparison
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Fever, Arthralgia/arthritis ... , Skin rash ± odynophagia ... Disease #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... maculopapular rash ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(sJIA) • Adult-onset ... Still disease ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
diseases: SLE+++, Adult-onset ... Still disease, ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Treatment of giant ... cell arteritis ... #GCA #Treatment ... #Management #Relapses ... #Indications #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Treatment - Mild ... #onset #Stills ... AOSD #diagnosis #rheumatology ... #management
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
rarely occurs in adults ... , Tachycardia, Arthritis ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... vasculitis in older adults ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... refractory disease Arthritis ... #management #pharmacology ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... common in Asia • HLA-B51 ... , AS Treatment: ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
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