15 results
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& hemorrhagic rash ... ; symptoms of shock ... disseminates in blood ... fetal blood vessel ... #Immunization #peds
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... and gut, which causes ... #clincial #peds ... #adrenal #calcifications ... #infant #NEJM #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Abdominal pain (20%) Renal ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... 21-OHD in the adrenal ... Signs/Symptoms/Complications ... endocrinology #peds
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
Pathogenesis and clinical ... artery Backup of blood ... retroperitoneal masses ... Obstruction of blood ... Pathophysiology #Signs #Symptoms
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Dermatomyositis Clinical ... : • Triad of symptoms ... urine • Other symptoms ... UA positive for blood
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... depressed) • Renal ... anaphylaxis, toxins/meds ... O2 delivery • PE ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... depressed) • Renal ... anaphylaxis, toxins/meds ... O2 delivery • PE ... #differential #causes
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... Neurological symptoms ... elevated white blood ... the underlying cause
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... endothelial lining of blood ... periumbilical region), nausea ... Intussusception - Renal ... Diagnosis #Signs #Symptoms