29 results
diagnosis management photo dermatology differential nephrology rheumatology criticalcare radiology classification infection neurology overview pediatrics renal rhabdomyolysis shock skinrash treatment 21hydroxylasedeficiency
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... acid lipase is critical ... and gut, which causes ... #clincial #peds ... #infant #NEJM #
Dermatomyositis A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of ... dermatomyositis ... 1) heliotrope rash ... Gottrons #Papules #Clinical
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... (blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... Men • ~50% of cases
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... heavy metals), Critical ... Shellfish poisoning, Meds ... , Polymyositis/dermatomyositis ... Neuromuscular #Weakness #Causes
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
rapidly evolving rash ... marine microbiota & causes ... , hypotension, rash ... immunosuppressive meds ... dermatology #legs #clinical
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... immobility • Critical ... infarction, Acute renal ... Subacute to Chronic Causes ... Inflammatory myopathy: dermatomyositis
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Secondary Causes ... based on repeat clinic ... multi-drug resistance) Renal ... • Bilateral RAS ... • Unilateral RAS
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... 21-OHD in the adrenal ... as "congenital adrenal ... endocrinology #peds
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... : Polymyositis/Dermatomyositis ... Clinical Features ... perfusion → renal ... Diagnosis #Management #causes
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
Management Summary CLINICAL ... Nephritic syndrome (Casts ... • Often severe renal ... • Vasculitic rash ... available • Renal
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