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diagnosis differential hematology hemophagocytic hlh lymphohistiocytosis hemeonc hodgkins lymphoma myopathy myositis oncology summary treatment vasculitides vasculitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Immunosuppression • Autoimmune ... • Dyspnea • Fever ... ) Classification ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Vasculitis: • Fevers ... differential #diagnosis #rheumatology ... #classification
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Infections (e.g., EBV ... Malignancies ▪ Autoimmune ... Infections, malignancy, autoimmune ... #Hematology #HemeOnc
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Symptoms: • Gottron rash ... Overlap Syndrome: Fever ... • ANA < 20 % IBM ... statins - probably caused
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