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diagnosis dermatology differential sle druginduced management manifestations mucocutaneous papulosquamous pathophysiology rheumatology signs symptoms table vesicular vesiculobullous
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... NPSLE rare, Malar rash ... Discontinuation of causal ... Positive in 60-80% of cases ... #sle #comparison
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash ... Differential Diagnosis Algorithm ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
response -> Subacute cutaneous ... hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... signs #symptoms #complications
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin Rash ... Differential Diagnosis Algorithm ... soles • Discoid Lupus ... Papulosquamous #SkinRash ... #causes
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