12 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) General: Fever ... Photosensitivity, Butterfly rash ... effusion, Restrictive lung ... Demyelinating syndromes ... Pericarditis, Endocarditis
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
and Rash - Diagnostic ... Algorithm Central ... Mycoplasma), Infective endocarditis ... angiomatosis, Sweet syndrome ... #Rash #Febrile
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... Constitutional symptoms ... , rales, interstitial
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... (45%) • Fever ... (28%) • Skin rash ... • New onset SLE
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... conditions: Autoimmune (SLE ... Clinical features: Fever ... in up to 30% of cases ... #comparison #infective
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... • Libman-Sacks endocarditis ... Induced Lupus: • Symptoms ... to: Arthritis, Fever ... and leukemia • Lung
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
verrucous) • Lung ... • Autoimmune (SLE ... positive in 90% of IE cases ... night sweats, fever ... Persistent bacteremia/fevers
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
, verrucous) - Lung ... • Autoimmune (SLE ... night sweats, fever ... Cholesterol emboli syndrome ... Persistent bacteremia/fevers
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... run-down or tired • Fevers ... in the adjacent lung ... of the affected lung ... , CCP, ANCA • HIV
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers ... vasculitis, and SLE ... Cryoglobulins • HIV