13 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) General: Fever ... , Vasculitis, Purpura ... effusion, Restrictive lung ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign ... , and SLE) • Urinalysis ... Cryoglobulins • HIV
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Induced Lupus: • Symptoms ... to: Arthritis, Fever
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... • CT: Halo sign ... of a "flu-like syndrome ... Constitutional symptoms ... , rales, interstitial
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Herpes Viruses (HSV ... Toxoplasmosis AUTOIMMUNE ... /VASCULITIS - Behcet ... (bulbar symptoms ... - small cell lung
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... Adrenals: • Lung ... from RTA type IV ... • Low-grade fever ... adrenalitis cases
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... , mucositis • Rash ... • Progressive symptoms
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... Predisposing conditions: Autoimmune ... (SLE/APLS), Malignancy ... #Endocarditis #comparison
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
or Haverhill fever ... of necrotizing vasculitis ... cancers, including lung ... include: infections (HSV ... PrathitKulkarni #Erythemas #comparison
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
verrucous) • Lung ... regurgitation • Autoimmune ... (SLE Libman Sacks ... night sweats, fever ... valvular disease • Vasculitis