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diagnosis differential clinical algorithm management video physicalexam cardiology neurology pocus radiology pathophysiology nephrology table treatment pharmacology pulmonary hematology ultrasound dermatology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria: 3 or more RBC ... disease - Alport syndrome ... pain hematuria syndrome ... hematuria: - RBC ... - Dysmorphic RBC
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... urine sediment - WBC ... /RBC casts ... Diagnosis #Algorithm #Causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... Myelodysplastic Syndromes ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... • Intrinsic RBC ... Extravascular #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... • Bilirubin: RBC ... • LDH: Heart, RBC
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... casts or dysmorphic ... RBCs in urine)?
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... Goodpasture's cause ... gross hematuria, RBC ... Pulmonary #Renal #Syndromes
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
Microscopy and Casts ... - Monomorphic RBCs ... - Dysmorphic RBCs ... - WBC Cast - ... RBC Cast - Fatty
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... Nephritic #Nephrotic #Syndromes
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