2653 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... aplastic anemia Treatment
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... gross hematuria, RBC ... Pulmonary #Renal #Syndromes ... diagnosis #management #treatment
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... or dysmorphic RBCs ... Nephritic #Nephrotic #Syndrome
Urine Microscopy and Casts - Image Atlas Key

- Squamous Epithelial Casts
- Transitional Epithelial Cells
- Renal Tubular
- Monomorphic RBCs ... - Dysmorphic RBCs ... Granular Casts - WBC ... Cast - RBC Cast
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
Hepatopulmonary Syndrome ... overperfusion + decreased RBC ... the left heart TREATMENT ... only definitive treatment ... resolution of syndrome
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Thalassemia • RBC ... Disorder • RBC
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... Nephritic #Nephrotic #Syndromes
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Drug-associated, PCH, Evans Syndrome ... 3) Internal (RBC ... Smear ↑ abnormal RBCs
Urinalysis Interpretation (UA)

Bacteria, Leukocyte esterase, WBC, Nitrite, RBC, Epithelial 
cells, pH

#Diagnosis #Urinalysis #Interpretation #Analysis
Leukocyte esterase, WBC ... , Nitrite, RBC,
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment