9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... cellular antigen, leading ... Complement activation ... sclerosis #Hypersensitivity ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... Allergen-specific lgE causes ... cell antigens, leading ... to complement activation ... allergy #table #classification
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Differential Diagnosis Algorithm ... Water and solute loading ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... cell surfaces causes ... because T-Cell activation ... #Hypersensitivity ... Reactions #Types #Classification
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Cause - Decreased ... gastrointestinal osmotic gradient ... Differential #Diagnosis #Algorithm ... Pathophysiology #Nephrology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... sympathetic + ADH activation ... Exclude other AKI causes ... Classification: ... Syndrome #Hepatology #Nephrology
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
Burning, shooting, gnawing ... Pain #Mechanisms #Neurology ... Differential #Diagnosis #Algorithm ... #Causes
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
channels open leading ... Vaughan Williams Classification ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... vasculitis • Hypersensitivity ... diagnosis #types #classification