28 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... #Classification ... Allergy #Diagnosis #Reactions
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... cell antigens, leading ... to complement activation ... Acute transfusion reaction ... #table #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... , leading to an ... because T-Cell activation ... #Types #Classification
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Anaphylaxis is a Type ... hypersensitivity reaction ... anaphylaxis is mast cell activation ... Inappropriate mast cell activation ... cells • ANS activation
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... Allergic reaction ... because T-Cell activation ... ivy) #TypeIV #Type4
In July 2015 the ACC/AHA proposed and published an algorithm to help stratify cardiac arrest patients
and published an algorithm ... emergent cath lab activation ... CardiacArrest #Algorithm ... CathLab #NSTEMI #Activation ... Stratfication #Management
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... Intake (diet) - Activation ... Hypocalcemia #Diagnosis #Management ... #differential #algorithm
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
among other cell types ... (see “Cytokine Activation ... 22% - Infusion reaction ... #Pharmacology #Management
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
gets activated leading ... skin, and brain leading ... by endothelial activation ... Exposure of Type-IV ... lysoganglioside leading
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... severe lgE-mediated reaction ... Hemorrhagic → leading ... water #Shock #Classification ... #management #criticalcare