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diagnosis differential types criticalcare allergy hematology hemophagocytic hlh hypersensitivity lymphohistiocytosis overview pharmacology reactions rheumatology summary table allergic antiarrhythmics cardiology classes
Vasopressors and Inotropes - Pharmacology Summary Vasopressors Phenylephrine (alpha-1) • Increases BP, SVR • Risk of reflex bradycardia
first agent in shock ... • Higher doses cause ... line in septic shock ... dependent receptor activation ... Pharmacology #Summary #management
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
cytokines, complement activation ... COMMON CAUSES + ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT ... #Diagnosis #Management
Shock Classification Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... #Classification ... Types #diagnosis #management
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... #Classification ... types #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... , Hb), Hepatic dysfunction ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... #differential #causes ... #classification
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... #differential #causes ... #classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... cell antigens, leading ... to complement activation ... allergy #table #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
channels open leading ... Vaughan Williams Classification ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
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