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diagnosis allergy hematology hemophagocytic hlh hypersensitivity lymphohistiocytosis reactions table shock treatment allergic cold comparison criticalcare definitions differential dry erythematosus hemeonc
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... Type 1 - Mediators ... cell antigens, leading ... to complement activation ... allergy #table #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... nervous system (CNS) dysfunction ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... water #Shock #Classification ... #management #criticalcare
Shock Classification Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Types #diagnosis ... #management #cold
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... immune reaction, leading ... because T-Cell activation ... #Classification
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... genetic immune dysfunction ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... by uncontrolled activation ... Types of HLH • ... MAS-HLH: Macrophage Activation ... uncontrolled immune activation
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... • Pancreas: Type ... complement • Classification ... #Rheumatology
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