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diagnosis reactions rheumatology allergy hemophagocytic hlh hypersensitivity lymphohistiocytosis allergic blood comparison definitions differential disorders erythematosus gammopathy hemeonc histiocytosis hypertension igg4
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... Allergen-specific lgE causes ... antigens, leading ... to complement activation ... allergy #table #classification
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... , Hb), Hepatic dysfunction ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... surfaces causes ... exposure to allergen causes ... activation takes ... #Classification
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... multifactorial mechanisms Hematologic ... pulmonary Langerhans cell ... #Differential #Causes
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... • Pancreas: Type ... complement • Classification ... #Rheumatology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
hematopoietic cell ... symptoms, unexplained hematologic ... Diagnosis and classification ... to 50% of PTLD cases ... oncology #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... Persistent fever, organ dysfunction ... Types of HLH • ... #Hematology #HemeOnc
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Pager Summary Type ... determines blood type ... potassium from lysed cells ... Transfusions #diagnosis #management ... #hematology #reactions
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Kikuchi disease • Type-I ... Angioimmunoblastic T-cell ... mild cognitive dysfunction ... : • Chronic B-cell
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
, a type of dendritic ... various tissues, leading ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... Histiocytosis #Diagnosis #Management
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