7 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... →Activation of CD8 ... IFN-y) → Excessive activation ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... lymphohistiocytosis (HLH ... nervous system (CNS) dysfunction ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... excessive macrophage activation ... genetic immune dysfunction ... / Diagnosis: HLH ... Lymphohistiocytosis #diagnosis #management
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... by uncontrolled activation ... Persistent fever, organ dysfunction ... : Macrophage Activation ... uncontrolled immune activation
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... cell antigens, leading ... to complement activation ... types #allergy #table ... #classification
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... Types #diagnosis #management ... warm #wet #dry #table