138 results
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
anaphylaxis is mast cell activation ... Inappropriate mast cell activation ... cells • ANS activation ... pathophysiology #immunology
#Interlukins
#Immunology
#Interlukins #Immunology
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
changes during DCs activation ... adaptive #immunity #immunology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
of antibodies, activation ... pathophysiology #immunology
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Viruses: HSV (reactivation ... Viruses: HSV (reactivation ... Viruses: CMV (reactivation ... ), VZV (reactivation ... ), CMV (reactivation
#Entire #basic #immunology #medical #rheumatic #hypersensitivity #immunity
Entire #basic #immunology
X-linked Severe Combined Immunodeficiency (SCID): Pathogenesis and clinical findings

#SCID #SevereCombinedImmunodeficiency #XLinked #pathophysiology #immunology
pathophysiology #immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
because T-Cell activation ... HypersensitivityReaction #Allergy #Immunology
Inflammatory, Immunologic, and Pathobiologic Features Leading to Severe Asthma. #Pathophysiology #Asthma #Mechanism #Leukotriene #Type2 #Inflammatory #Immunologic
Inflammatory, Immunologic ... #Inflammatory #Immunologic
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
lectin pathway activation ... and meninges -> Activation ... pathophysiology #immunology