17 results
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Phase I - Initial ... Vaughan Williams Classification ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
Classification of COVID-19 Disease States and Potential Therapeutic Targets

Viral Response Phase -> Host Inflammatory Response Phase
Stage
Classification of ... Viral Response Phase ... II (Pulmonary Phase ... #Progression #Classification ... #Diagnosis #Pathophysiology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
anaphylaxis is mast cell activation ... Inappropriate mast cell activation ... => Immediate Phase ... cells • ANS activation ... #Anaphylaxis #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... • ↓ slope of phase ... Inhibit B.adrenergic activation ... #Pharmacology #Classification ... #Classes #pathophysiology
The pathogenesis of idiopathic pulmonary fibrosis. 1 – In an initiating phase, there is lung alveolar
an initiating phase ... as αvβ6, and a phase ... its cleavage and activation ... At this final phase ... #IPF #Pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
to complement activation ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Course: Immediate-phase ... minutes, Late-phase ... to complement activation ... allergy #table #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
and Management Algorithm ... between the above phases ... absent the risk of reactivation ... HepatitisB #HBV #Algorithm
African Trypanosomiasis - Trypanosoma brucei gambiense & Trypanosoma brucei rhodesiense Life Cycle
1) Tsetse fly takes a
blood during acute phase ... undetectable in latent phase ... #Trypanosoma #LifeCycle ... #diagnosis #pathophysiology