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diagnosis differential clinical hepatology management hepatic liver pocus pharmacology ultrasound causes algorithm hematology pathophysiology anticoagulation doac signs neurology radiology table
Anticoagulant specific factor inhibition. #anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban #Xarelto #apixaban
clotting #INR #heparin ... warfarin #coumadin #rivaroxaban ... #Xarelto #apixaban
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
Anticoagulants • Heparin ... Unfractionated heparin ... Xa Inhibitors: Rivaroxaban ... , Apixaban, Edoxaban
Choice of anticoagulant for treatment of pulmonary embolism • Malignancy - LMWH • To avoid parenteral
parenteral therapy - Rivaroxaban ... ; apixaban • Once ... oral therapy - Rivaroxaban ... edoxaban; VKA • Hepatic ... Gl bleed - VKA, apixaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparin, Fondaparinux ... anticoagulant (e.g. rivaroxaban ... - Rivaroxaban ... DOAC #Dabigatran #Apixaban ... #Rivaroxaban #Fondaparinux
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Warfarin - 100% Hepatic ... , 0% Renal Apixaban ... - 75% Hepatic, ... , 50% Renal Rivaroxaban ... - 65% Hepatic,
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... Edoxaban (Lixiana), Rivaroxaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... Xa inhibitors - Apixaban ... , rivaroxaban -
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
Unfractionated Heparin ... Molecular Weight Heparin ... Bivalirudin, Dabigatran, Apixaban ... Betrixaban, Edoxaban, Rivaroxaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #inhibitor #Apixaban ... #Rivaroxaban #Edoxaban ... #heparin #pathway
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Xa inhibitors - Rivaroxaban ... , apixaban, edoxaban ... unfractionated heparin ... cause e.g. heparin ... thrombin inhibitors, heparin
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