362 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Bridging #Dosing #Oral ... Anticoagulation #Dabigatran ... #Apixaban #Rivaroxaban
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
Novel (or Direct) Oral ... Anti-Coagulants • Rivaroxaban ... • Apixaban • Dabigatran ... management #Direct #Oral
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Warfarin, Apixaban, Dabigatran ... , Rivaroxaban ... - Resume #Oral
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Clearance of Oral ... Hepatic, 25% Renal Dabigatran ... Hepatic, 50% Renal Rivaroxaban ... Pharmacology #Clearance #oral
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Fondaparinux, and Novel Oral ... anticoagulant (e.g. rivaroxaban ... - Rivaroxaban ... LMWH #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Apixaban, Edoxaban or Rivaroxaban ... modified factor Xa • Dabigatran ... Reversal #NOAC #Oral
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... of Therapy • Dabigatran ... Apixaban, Edoxaban, Rivaroxaban
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Pharmacology Warfarin - Dabigatran ... - Rivaroxaban - ... comparison #table #dabigatran ... #rivaroxaban #apixaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
warfarin #coumadin #rivaroxaban ... apixaban #Eliquis #dabigatran
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
Sheet • Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban