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hepatology management algorithm alkaline coccidioidomycosis infectiousdiseases oncology pathophysiology phosphatase abnormal aflp anemia biliary cholangitis cirrhosis classification cocci disorders elevation enzymes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... • Liver (80%) ... Intestine - Other causes ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... candidate) - Bone ... #Diagnosis #Causes ... #Workup #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... syndrome, Congestion/CHF ... : Bone, first trimester
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... Most cases diagnosed ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
• CNS symptoms ... Get an LP and imaging ... values supporting hematologic ... Bone marrow biopsy ... #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral ... Pregnancy #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... Areas of diagnostic ... Abnormal #Algorithm #Hepatology ... #Differential # ... Diagnosis
Coccidiomycosis - Diagnosis Diagnosis: • Mildly elevated peripheral WBC, Eosinophilia (25%), Elevated ESR, Procalcitonin normal (95%) •
- Can involve liver ... , pericardium, bone ... Puncture only if CNS symptoms ... Coccidioidomycosis #cocci #Coccidioides ... #Diagnosis #workup
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... PBC Signs and Symptoms ... obstruction • ALP ... bile ducts Differential ... #workup #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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