19 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... • Liver (80%) ... Intestine - Other causes ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... candidate) - Bone ... #Diagnosis #Causes ... #Workup #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Vascular Causes ... syndrome, Congestion/CHF ... cell lung CA, lymphoma ... : Bone, first trimester
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
the spleen or liver ... Diagnosis of B-Symptoms ... • Other hematologic ... #differential # ... hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
• CNS symptoms ... Get an LP and imaging ... values supporting hematologic ... Bone marrow biopsy ... #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... PBC Signs and Symptoms ... obstruction • ALP ... Endocrinopathy, Lymphoma ... #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral ... Pregnancy #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential # ... Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... and secondary lymphoid ... of large cell lymphoma ... #Leukemia #Hematology ... #Oncology #Diagnosis