18 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... and petechiae Causes ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Most common symptoms ... symptoms - Pain ... #Algorithm #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... • Bone marrow ... Management #treatment #hematology ... #oncology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology ... #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Workup History ... pylori test (GI symptoms ... candidate) - Bone ... #Causes #Workup ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... syndrome, Congestion/CHF ... : Bone, first trimester ... #algorithm #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... Symptoms: • Malaise ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
cell lymphoma, ALK ... (MC are skin, bone ... advanced stage + B symptoms ... pattern: mimics NS CHL ... than one • Rare cases
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... PBC Signs and Symptoms ... obstruction • ALP ... Differential Diagnosis ... #workup #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Pure red cell aplasia ... Warm AIHA • Bone ... #workup #oncology ... #hematology