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diagnosis hematology management neurology syndrome apml classification differentiation encephalitis encephalopathy hepatitis hodgkins infections injury leukemia liver lymphoma mds meningitis myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
coagulopathy common • Imaging ... Diagnosis: >3 symptoms ... initiation • Differential ... sepsis), PE, DAH, CHF ... #oncology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Coltivirus Symptoms ... : • Acute meningeal ... Gram stain: Previous ... Singh @rav7ks #CNS
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Vascular Causes ... syndrome, Congestion/CHF ... hemolysis) • ALP: Bone ... #hepatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Transplantation including bone ... Neurological symptoms ... : Acute onset 2 ... Reversible course Differential ... the underlying cause
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... blood count with differential ... factors (examples: G-CSF ... #oncology
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