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Acyclovir - Pharmacology Summary

• Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of

Acyclovir - Pharmacology ... Nucleoside analog - selectively ... TheIDtrivia #Acyclovir

Hutchinson's Sign
- A sign of ophthalmic zoster
- Multiple crusted vesicles in distribution of

of ophthalmic zoster ... ophthalmology - Tx w/ acyclovir ... #HSV #Herpes #zoster

NSAID Selectivity Spectrum
COX-2 Selective NSAID - Celecoxib
• Increased risk for CV events
• Decreased risk

NSAID Selectivity ... effects #NSAIDs #selectivity

The algorithm below shows how pre-test probability could be combined with various criteria to determine which

require empiric acyclovir ... The risk of acyclovir-induced ... favor the use of acyclovir ... -Acyclovir is nephrotoxic ... require empiric acyclovir

Urine Microscopy - Kidney Stones and Crystals

Uric Acid, Cystine, Hippurate, Cloth Fiber, Tyrosine, CaOx, CaP,

CaCO3, Struvite, Acyclovir

Blurry vision in a patient with HIV/AIDS
Anterior Segment:
• Herpes zoster ophthalmicus
• Keratitis (HSV, Staph,

Segment: • Herpes zoster ... • Progressive Outer

Varicella (Chickenpox) - Crops of vesicles in various stages of healing

Treatment
• Healthy g 12

Immunocompromised or > 12: Acyclovir

Heparin and Low Molecular Weight Heparin (LMWH)–Mediated Inactivation of Thrombin or Factor Xa
- Interaction

- LMWH selectively

Herpes Zoster Treatment
Acyclovir x 7-14 days
- Age > 50
- Severe rash or pain
-

Herpes Zoster Treatment ... Acyclovir x 7-14 ... : No impact of acyclovir ... UTSWIMchief #Herpes #Zoster

Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the

Herpes Zoster Mandibularis ... diagnosis of herpes zoster ... Dermatology #Herpes #Zoster

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