Heparin and Low Molecular Weight Heparin (LMWH)–Mediated Inactivation of Thrombin or Factor Xa
- Interaction of antithrombin with heparin and LMWH is mediated by a pentasaccharide sequence.
- Unfractionated heparin accelerates interaction of antithrombin with both thrombin and factor Xa.
- LMWH selectively accelerates interaction of antithrombin with factor Xa
#Heparin #LMWH #Pharmacology