11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Pain Rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... rheumatology #approach #workup ... #differential #
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... dz difficult to see ... • Differentiate ... #Disease #differential ... diagnosis #causes #hematology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... and fingers, or pain ... the face (many differential ... #diagnosis #sle
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Demand: Stress / Pain ... Beta-Agonists, ↑ work ... Leukemia/Lymphoma), Diabetes ... Lactic #Acidosis #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... again we might see ... Join the resistance ... • Type B1: - Diabetes ... Acidosis #Elevation #Differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... , and low back pain ... Arthritis #laboratory #workup
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... lesions • Severe pain ... Autoimmune Vasculitis (lupus ... deficiency Work ... Algorithm #Causes #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... • Fever is the main ... SJIA], systemic lupus ... erythematosus [SLE ... Triglycerides • ↑ Lactate