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diagnosis management hematology blood reactions syndrome activation antinxp2 antinxp2dm classification clinical cryofibrinogenemia cutaneous dermatomyositis differential erythematosus eschar macrophage mas mucormycosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Associated with skin ... severe disease Treatment ... Summary #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... • Fibrin split products ... thrombi including retinal ... cryoglobulins • Negative causes ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... Fibrin degradation products ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
, DIC, hypoTN, renal ... Causes purpura & ... TRALI): Leading cause ... infections with skin ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, DIC, hypoTN, renal ... Causes purpura & ... TRALI): Leading cause ... infections with skin ... diagnosis #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
drug injections, renal ... malnutrition, HIV, SLE ... Mucormycosis #Eschar #dermatology ... #skin #clinical ... #photo
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Muscle atrophy may cause ... • Clear cell renal ... positive patients Treatment ... diagnosis #management #rheumatology ... #dermatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
• Inner ear • Skin ... such as: • SLE ... Heart failure • Renal ... affected tissue Treatment ... Polychondritis #rheumatology
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