11 results
diagnosis hematology algorithm causes hemolytic rheumatology systemic agglutinin autoimmune classification cold disease erythematosus extravascular high hyperkalemia intravascular monoclonal naildisorders nonpalpable
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic ... Anemia (AIHA) ... Autoimmune • Lupus ... #Anemia #AIHA # ... Diagnosis #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... - Autoimmune (AIHA ... usually IgG) (e.g. lupus ... Extravascular #Causes #differential ... #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Hypersplenism • Secondary ... RA, SLE, PRV, Chronic ... Bleed • Hemolysis ... #Differential #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... genotypes): SS, SC, SE ... #Anemia #Differential ... Diagnosis #Algorithm #workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Primary Secondary ... lymphoproliferative disorder Secondary ... younger pts) Differential ... #anemia #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic renal ... #dermatology #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
anemia Indirect ... WBC count and differential ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Coagulopathy) SMZL: • AIHA ... • Coombs (-) hemolytic ... anemia due to cold ... IgG • Lupus anticoagulant ... #Monoclonal #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... - CTD (SLE)
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... APLA/LAC: • Renal ... Hematologic: • AIHA ... lymphopenia, low PLT • Anemia
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