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diagnosis hematology classification apml causes differentiation erythematosus gap globulin hodgkins hyperkalemia monoclonal paraproteinemias potassium protein proteingap rheumatology syndrome systemic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Workup: • Full ... - WBC may be high ... Immunohistochemical studies (to differentiate ... #oncology #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... permanent alopecia Differential ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... #Monoclonal #Differential ... #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Attempt if high ... initiation • Differential ... Anaphylaxis, Acute Renal ... APML #diagnosis #management ... #hematology #oncology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
diseases: syßtemic lupus ... Renal resistance ... Advanced renal insufficiency ... End-stage renal ... #Diagnosis #High
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... cancers, HCC, renal ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
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