10 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... RA, SLE, PRV, Chronic ... Reticulocytosis • Renal ... #Differential # ... Algorithm #Causes #Hematology
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
: Lactic Acidosis ... Ketoacidosis, Renal ... loss of bicarb, Renal ... GI loss of H+, Renal ... Disorders #Evaluation #workup
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... liver Failure, Renal ... #Acidosis #Differential
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic renal ... Systemic #Secondary #dermatology ... #Differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... contribution of liver or renal ... 30mmHg) - Severe anemia ... deficiency - Renal ... lactate production Renal
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... APLA/LAC: • Renal ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... WBC count and differential ... the presence of renal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Acidosis B. ... diseases: syßtemic lupus ... Renal resistance ... Advanced renal insufficiency ... End-stage renal
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... cancers, HCC, renal ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology