45 results
Asthma
Chronic lung disease characterized by airway inflammation, airway and variable expiratory air flow obstruction
There are 2
obstruction: • FEV1 ... 0.70 or lower • FEV1 ... Reversibility on spirometry ... • Increase of FEV1 ... or greater in FEV
Spirometry - PFT Interpretation Algorithm

- BWH Medicine Chiefs @BrighamChiefs

#Spirometry #PFTs #Interpretation #Algorithm #diagnosis #differential #pulmonary #function
Spirometry - PFT ... BrighamChiefs #Spirometry ... differential #pulmonary #function
Asthma vs COPD Presentation and Diagnosis
Asthma:
 • Epidemiology: Age usually < 45, History (personal or family)
Variably abnormal spirometry ... - FEV1/FVC < 70% ... bronchodilator, Spirometry ... Persistently abnormal spirometry ... - FEV1/FVC < 70%
Classic (2009) Spirometric GOLD Classification of COPD Severity Based on Postbronchodilator FEV
#Diagnosis #Pulmonary #COPD #GOLD #Staging
Classic (2009) Spirometric ... Postbronchodilator FEV ... Classification #FEV1
Pulmonary Function Testing: Flow Volume Loop Patterns
 • Variable extra-thoracic obstruction - truncated or flattened inspiratory
Pulmonary Function ... and persevered FEV1 ... flow with reduced FEV1
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC channel function ... Aldosterone Receptor Function ... Pathophysiology #Pharmacology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... corticosteroid; FEV1
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
potassium, and renal function ... Dosing #Conversion #Pharmacology
Classification of Some Antimicrobial Agents by Their Sites of Action
Inhibitors of metabolism: Sulfonamides, Trimethoprim
Inhibitors of cell
of nucleic acid function ... cell membrane function ... sites #action #pharmacology
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Wall Synthesis or Function ... Acid Synthesis or Function ... Sites #Action #Pharmacology