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diagnosis hematology algorithm causes management pruritus secondary systemic apml bandemia classification differentiation hodgkins lymphoma mds monoclonal myelodysplasia myelodysplastic neutrophil paraproteinemias
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... renal failure/uremia ... Hyperthyroidism CBC ... secondary #systemic #generalized ... #dermatology #Differential
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Neutrophil (Normal) Differential ... #differential # ... #CBC #hematology ... #pathophysiology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
renal failure/uremia ... Hyperthyroidism CBC ... & Differential: ... secondary #systemic #generalized ... #dermatology #Differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
+Organomegaly+↑RBC ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... platelets - WBC ... Immunohistochemical studies (to differentiate ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... • Aplastic Anemia ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
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