11 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip ... • Differentiate ... #diagnosis #causes ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... Diagnosis Framework ... etc) - Viral: HIV ... folate def - Bone ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Drug induced - Bone ... #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... candidate) - Bone ... #Diagnosis #Causes ... #Workup #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Intra-articulation fracture ... - Aneurysmal bone ... #physicalexam
Stork Test 

The stork test evaluates for a stress fracture of the pars interarticularis in the
evaluates for a stress fracture ... places hands on hips ... Lumbar #spine #PhysicalExam ... clinical #video #sports ... #msk #orthopedics
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... e.g., congenital hip ... Joint #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... Bone/Joint Causes ... Leg Pain: • Fracture ... extremity #msk #physicalexam
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... characteristic feature ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Entities That Can Feature ... Splenic Marginal Zone ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology