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diagnosis hematology management differential oncology acid acidbase apml base bloodgas common cvid differentiation disorders gas hypogammaglobulinemia immunodeficiency immunology interpretation leukemia
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm CXR Abnormal: • Pulmonary Sequestration • Congenital Adenoid Cystic
Causes of Pediatric ... CXR Abnormal: ... Vascular Compression Syndrome ... #Causes #Peds # ... Pediatrics #Pulmonary
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
glycol (present in IV ... D-lactate (short bowel syndrome ... Anxiety, pain, fever ... Classically” noted with pulmonary ... Summary #Nephrology #ABG
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... - 80% have fever ... febrile, give abx ... diagnosis #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... common • Imaging: CXR ... - pulmonary opacities ... • Steroids: IV ... Differentiation #Syndrome
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
50,000 patients • Avg ... Low serum IgG level ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Disease: • 10%-15% Pulmonary ... risk PE, Pulmonary ... vasculitis: 10%-16% Liver ... #Rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Philadelphia - BCR-ABL ... -> AML: Blast crises ... develop leukostasis syndrome ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome
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