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REBEL Review 4 & 5: Paralytic & Vasopressor Dosing 

Paralytic Agents:
 - Succinylcholine (Depolarizing Agent)
5: Paralytic & Vasopressor ... resuscitation #table ... #criticalcare # ... pharmacology #dosing ... #medications #Comparison
Simplified Vasopressors and Inotropes Comparison Chart
MAP = CO x SVR
Dobutamine - Norepinephrine - Epinephrine - Phenylephrine
Simplified Vasopressors ... and Inotropes Comparison ... Chart MAP = CO x SVR ... #table #criticalcare ... #pharmacology
Vasopressors and Inotropes - Comparison Table
Activity: Alpha-1, Beta-1, Dopamine, SVR, HR, CO, BP
Phenylephrine
Vasopressin
Norepinephrine
Epinephrine
Dopamine
Dobutamine
Isoproterenol
Milrinone

- Dr. Eric Strong
Vasopressors and ... Table Activity: ... Beta-1, Dopamine, SVR ... #table #pharmacology ... #criticalcare
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors and ... Inotropes #management #criticalcare ... #summary #comparison ... #table #pharmacology ... #indications
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Inotropes - Pharmacology ... Summary Vasopressors ... first agent in shock ... line in septic shock ... #medications
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Common Vasopressors ... Cardiac ischemia #Vasopressors ... #Inotropes #comparison ... #table #pharmacology ... #criticalcare
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
hasankazmi01 #Vasopressors ... #Drugs #pharmacology ... #inopressors #diagnosis ... #management #comparison ... #table
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... and Management Summary ... Prepare • Full Set ... Neurogenic >> Vasopressors ... #Summary #criticalcare
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... Diagnosis Framework ... uw_IMresidency #Shock ... #table #comparison ... #criticalcare
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Anticoagulant Medications ... Acute DIC - Septic shock ... #table #comparison ... #diagnosis #hematology