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diagnosis management treatment criticalcare differential infectiousdiseases algorithm betadglucan biomarkers cardiology cardiomyopathy curves galactomannan guyton ia infections mycoses peripartum undifferentiated
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
specificity for invasive ... cut-offs defined in clinical ... colonization vs invasive ... non-neutropenic pts, SOT ... Galactomannan #diagnosis #comparison
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Invasive Aspergillus ... immunosuppression (eg ... HIV/AIDS, CGD) Clinical ... presentations: • Pulmonary ... Management #treatment #fungal
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... Failure, Toxins/Medications ... • Obstructive: Pulmonary ... Embolism, Tension ... ) UOP > 0.5 cc/kg
Approach to Undifferentiated Shock - OnePager Summary Shock occurs when there is inadequate blood flow (CO) &
Cardiac Tamponade, Pulmonary ... Embolism, Outflow ... Pipes Problem (↓ SVR ... amniotic or fat embolism ... thyrotoxicosis), Medications
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
cardiomyopathy • Pulmonary ... embolus 3. ... remains unknown • Final ... Pts: cardiogenic shock ... support for patients clinically
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... stain of clinical ... ASPERGILLOSIS • Aspergillus ... fever • Septic shock ... of 30% to 40% Invasive
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