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diagnosis management oncology leukemia chronic differential hemeonc heparin hit induced lymphocytic treatment agglutinin anemia causes coagulation cold dic disease disseminated
Approach to suspected Heparin-Induced Thrombocytopenia (HIT) • Suspected HIT Algorithm • "4 T's" clinical probability score:
• "4 T's" clinical ... - Thrombosis ... #HIT #hematology ... #diagnosis #4Ts ... #algorithm
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... and Management Algorithm ... TMA: Unexplained thrombocytopenia ... Reticulocytes, smear ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
5-10d, venous (DVT ... Diagnosis: • Clinical ... Management: • D/c all ... non-heparin A/C if clinical ... Management #Treatment #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... infiltrates (anemia, thrombocytopenia ... • Peripheral smear ... Develops in treated pts ... #Leukemia #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... IgM) • Blood smear ... malignancies -> CLL ... significance (MGUS), CLL ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... • Peripheral smear ... immunophenotype Clinical ... fludarabine) 3) Monoclonal ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... Orange or Hep C Clinical ... • Peripheral smear ... Neutropenia, anemia, thrombocytopenia ... workup #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... • Peripheral smear ... - bleeding or thrombosis ... presence of large thrombosis ... treatment #management #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Organomegaly+↑RBC/plt+, ↑thrombosis ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
erythromelalgia • Thrombosis ... MI, stroke, DVT/ ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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