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clinical differential skin canimorsus capnocytophaga cell chronic classification cll cutaneous eschar hemolysis hodgkins leukemia lymphocytic lymphoma management mds monoclonal mucormycosis
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... hemolytic-uremic syndrome (ST-HUS ... macroangiopathic hemolytic anemia ... #hematology #hemolysis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... activity is the diagnostic ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... Hyperviscosity (Thrombosis ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Canimorsus Skin Rash ... Bandemia, AKI. ... the key to the diagnosis ... #dermatology #clinical ... #photo
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... • Neutropenia, anemia ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... hem CA, HSCT, SOT ... trauma, aplastic anemia ... Mucormycosis #Eschar #dermatology ... skin #clinical #photo
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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