11 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... Complications and Treatment ... #SideEffects #Table ... #Diagnosis #Pharmacology ... #Oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Venous disease (SVC ... , dural sinus thrombosis ... Behcet disease) Differential ... Arthritis, AS Treatment ... #signs #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : >3 symptoms, or ... initiation • Differential ... management #hematology #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... : • Triad of symptoms ... urine • Other symptoms ... per day until stable
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
(e.g., long QT syndrome ... Digoxin toxicity Symptoms ... Diagnosis: • PAC ... more intensive treatment ... #differential #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Neurological symptoms ... Reversible course Differential ... Cerebral venous thrombosis ... epilepticus Treatment ... underlying cause • Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology ... #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... acute coronary syndrome ... #diagnosis #differential ... #table #foamed ... icu #clinical #pharmacology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
Consider refeeding syndrome ... i.e. infections, thrombosis ... and vasomotor symptoms ... gastroenterology #diagnosis ... #differential