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Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... causes development ... T-Cell response ... Allergic reaction ... exposure, because T-Cell
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... with cytotoxic T ... and cytotoxic T ... Hypersensitivity #Types #Classification
Allergic Contact Dermatitis - Erythematous, indurated, scaly plaques - T-cell mediated, delayed-type hypersensitivity response to exogenous
Allergic Contact ... scaly plaques - T-cell ... Contact #Dermatitis #Allergic ... #Allergy #Dermatology
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
cytokines Common causes ... infection - Allergic ... : - B or T cell ... CD3-CD4+ T cells ... ) - Allergic bronchopulmonary
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... T-cells recruit ... reactions #types #allergy ... #table #classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
surfaces causes ... it is entirely T-Cell ... T-Cell response ... exposure, because T-Cell ... #Types #Classification
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Angioedema: • Mast cell-mediated ... in > 90% of cases ... is key • Mast cell-mediated ... #Angioedema #Classification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Target: Modified cell ... Immunological Mediator: Th Cells ... #Types #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
Sickness) Type IV T-Cell-Mediated ... reactions #Types #Classification ... #Allergy #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... CD10 - T-cell ... or λ), Smudge Cells ... Thrombocytosis - T-cell ... Differential #Diagnosis #Algorithm
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