21 results
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
antigen-surface complex ... Antigen binds receptor ... (i.e. heparin) binds ... antigen-surface complex ... Allergy #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
specific allergen binds ... with cytotoxic T ... Antigen-antibody complexes ... and cytotoxic T ... Classification #Pathophysiology
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
Activated T cells ... to the T-cell receptor ... histocompatibility complex ... depending on the T-cell ... ImmuneResponses #immunology #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
activate naive CD4 T ... cells. ... These T cells then ... binds the FceRI ... #asthma #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
other tissue • T ... to CD4+ helper T ... B cellsT cell-independent ... co-receptor complex ... Humoral #Immunity #pathophysiology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Evaluation of Leukocytosis ... , T cells, and natural ... Neutrophil bands ... Morphologically: absence of complete ... LEUKEMOIDREACTION #BANDS
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
dysfunction of dendritic cells ... , B-cells, T-cells ... production of immune complexes ... Auto-reactive T-cells ... Erythematosus #SLE #Pathophysiology
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
peptides to Helper T ... cells -> Helper ... T cells release ... Exposure -> Antigen binds ... Rhinitis #Rhinorrhea #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
and induce mast cell ... Pre-formed lgE binds ... allergen-antibody complex ... Allergen-antibody complexes ... Allergy #Immunology #pathophysiology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Differential Diagnosis Algorithm ... : • Squamous cell ... fungoides (cutaneous T-cell ... Viral - Herpes simplex ... Differential #Diagnosis #Algorithm