35 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T ... cytokines, which activate ... and cytotoxic T ... Hypersensitivity #Types #Classification ... #Pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... activate macrophages ... Allergy #Immunology #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... antigens and thereby activate ... naive CD4 T cells ... These T cells then ... #asthma #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... activity #Inflammatory ... #Inflammation #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
cells and activate ... B cellsT cell-independent ... neutralizing them - Activate ... Complement: Abs activate ... Humoral #Immunity #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
tissues where they activate ... activate Th1/cytotoxic ... T cells. ... T-cells recruit ... allergy #table #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... as common - T ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... /µL Workup • Screen
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... for the workup ... sensitivity for correct classification ... Thus, further testing ... #Differential #Algorithm
Hypoglycemia - Evaluation Algorithm
Interpreting Hypoglycemia Labs - the patient must be hypoglycemic at the time of
Hypoglycemia - Evaluation Algorithm ... at the time of testing ... Malignancy (islet cell ... Hypoglycemia #Evaluation #Algorithm ... #workup #diagnosis