37 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... CD10 - T-cell ... o CML - bcr-able ... Thrombocytosis - T-cell ... Differential #Diagnosis #Algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T ... cytokines, which activate ... and cytotoxic T ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... allergen-specific T-Cell ... exposure, because T-Cell ... activate macrophages ... Allergy #Immunology #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... antigens and thereby activate ... naive CD4 T cells ... These T cells then ... #asthma #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... activity #Inflammatory ... #Inflammation #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... activate Th1/cytotoxic ... T cells. ... T-cells recruit ... types #allergy #table
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
cells and activate ... B cellsT cell-independent ... neutralizing them - Activate ... Complement: Abs activate ... Humoral #Immunity #pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Algorithm INDICATIONS ... evaluation or workup ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... /µL Workup • Screen
The Spectrum of Tuberculosis

As shown in the graphic from our Primer, exposure to M. tuberculosis can
response, or acquired T-cell ... #Tuberculosis #Testing ... IGRA #Spectrum #Table ... #Subclinical #Active
Hypoglycemia - Evaluation Algorithm
Interpreting Hypoglycemia Labs - the patient must be hypoglycemic at the time of
Hypoglycemia - Evaluation Algorithm ... at the time of testing ... Malignancy (islet cell ... Hypoglycemia #Evaluation #Algorithm ... #workup #diagnosis