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diagnosis differential criticalcare management acidosis fever lactic acute anesthesia anesthesiology checklist classification criteria elevation falls fluids hematology icu immunecompromised immunocompromised
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• Septic shock ... with Shock: Sepsis ... • 49 million cases ... COMMON CAUSES + ... #Septic #Shock
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
30ml.kg-1 or blood lactate ... likely underlying cause ... ) or septic shock ... organ dysfunction ... devices could have caused
Decision tree of FALLS-protocol (Fluid Administration Limited by Lung Sonography). Lung Ultrasound in the hemodynamic assessment
tree of FALLS-protocol ... assessment of Shock ... , i.e. septic shock ... #algorithm #Lung ... #Fluids #POCUS
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... /hypoxemia/Sepsis ... Causes of Lactate ... syndrome - Sepsis ... - Cyanide - Propofol
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Cardiogenic & Septic ... Shock, Severe Anemia ... Microcirculatory dysfunction ... Drugs/Toxins: - Propofol ... Malaria, Late Sepsis
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
Life-threatening organ dysfunction ... caused by a dysregulated ... SHOCK is a subset ... shock are identified ... Serum lactate >2
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Causes of Acute ... • Fungal • Protozoa ... Continuous Bacteremia Septic ... Shock Acute Organ ... #causes
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... • Bacteremia/Septic ... Shock • Encapsulated ... or Neutrophil Dysfunction ... #Causes #Hematology
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