18 results
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... Action, Maximum Dose ... #Diuretics #Pharmacology ... #Comparison #Table ... #HalfLife #Dosing
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose ... Comparison. ... ACEInhibitor #ACEIs #Dosing ... #Conversion #Pharmacology ... #Table
Statins intensity, drug interactions, timing of administration and missed doses.

An overview of high, moderate and low
administration and missed doses ... #pharmacology #overview ... #review #dosing ... #medications #comparison ... #drugs #table
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
e.g. at lower doses ... #pharmacology #comparison ... #medications #dosing ... #drugs #table #
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
-24 hours post dose ... 12 hours post dose ... - Intermittent dosing ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... 10 g QD (adjust dose ... g QD; increase dose ... #medications #pharmacology ... #table #comparison
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
hyperpolarization - Dose-dependent ... amnesia • hypnosis • anesthesia ... amnesia • hypnosis • anesthesia ... #medications #pharmacology ... #comparison #table
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
immediate clinical team ... continuous CPR using ... small incremental dose ... Anesthesiology #Anesthesia ... Intraoperative #Checklist #Diagnosis
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag moving ... with surgical team ... #Hypotension #Differential ... Anesthesiology #Anesthesia ... Intraoperative #Checklist #Diagnosis
When assessing a patient with acute dyspnea during or shortly following a transfusion, it is challenging
acute dyspnea during ... challenging to differentiate ... #Diagnosis #Transfusion ... #TRALI #TACO #Comparison ... #Table