12 results
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
RA Rheumatic disorders ... • Rheumatoid arthritis ... • Inflammatory disorders ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... deficiency, ... laboratory ... hallucinations - Movement disorders ... MNCD #Dementia #Differential ... #Subtypes #Classification
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., meniscal tears ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... Amy Chung, MD, MSc ... #Classification ... pathophysiology #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... Skin Disease Classification ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... with: • Minimal laboratory
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
pathognomonic laboratory ... Behcet disease) Differential ... SLE, Reactive arthritis ... Giant retinal tears ... signs #symptoms #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... Mechanical/degenerative disorders ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... more time for the laboratory ... metabolic or endocrine disorders ... #laboratory #workup ... diagnosis #testing #Rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
#Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential # ... diagnosis #arthritis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... and often causes arthritis ... well as inner ear ... #diagnosis #rheumatology ... #classification